Z.C. is a 49-year-old man with autosomal dominant polycystic kidney disease (ADPKD). His kidneys are enlarged with multiple urine-filled cystic lesions. Z.C. is currently in a stage of renal insufficiency with a GFR of about 20% of normal. He suffers from recurrent urinary tract infections and chronic anemia. In counseling Z.C. about the risk of transmitting the disorder to his offspring, which of the following statements would be correct?

Question

Quizplus · Accepted Answer

Autosomal dominant inheritance means that each offspring of an affected parent has a 50% chance of inheriting the affected allele and developing the disease.

ZC Is a 49-Year-Old Man with Autosomal Dominant Polycystic Kidney