The therapy that most directly improves cardiac contractility in a patient with systolic heart failure is

Question

Quizplus · Accepted Answer

Digitalis directly improves cardiac contractility in patients with systolic heart failure. It works by inhibiting the Na+/K+ ATPase pump in myocardial cells, which increases intracellular calcium levels, leading to increased contractility. Afterload reduction and preload reduction may improve cardiac function indirectly, but they do not directly improve cardiac contractility. Beta-blockers can improve outcomes in systolic heart failure, but they do not directly improve cardiac contractility.

The Therapy That Most Directly Improves Cardiac Contractility in a Patient