In general, the best prognosis for long-term disease-free survival occurs with

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Acute lymphoblastic leukemia (ALL) typically has the best prognosis for long-term disease-free survival, especially in children. The five-year survival rate for children with ALL is greater than 90%, and even in adults, the five-year survival rate is often around 50-60%. This is partially due to advances in treatment, such as chemotherapy, stem cell transplantation, and targeted therapies.

The other options - CLL, AML, and CML - are all types of leukemia as well. However, CLL is typically a slower-progressing form of leukemia, and while patients may need ongoing treatment, they can often live for many years with the disease. AML and CML are more aggressive forms of leukemia, and while some patients may achieve long-term remission with treatment, the prognosis can be less favorable than with ALL.

In General, the Best Prognosis for Long-Term Disease-Free Survival Occurs