Delayed-type hypersensitivity reactions require participation by T lymphocytes.

Question

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Delayed-type hypersensitivity reactions involve activation of T lymphocytes, specifically CD4+ T helper cells and CD8+ cytotoxic T cells, which release cytokines and chemokines that attract and activate other immune cells like macrophages and neutrophils to the site of inflammation. This results in a delayed onset of the inflammatory response, typically occurring 24-72 hours after exposure to the allergen or antigen.

Delayed-Type Hypersensitivity Reactions Require Participation by T Lymphocytes