Exhibit 26-5
Refer to the data below to answer the following question(s):
The octapeptide saralasin is a specific antagonist of angiotensin II.A derivative of saralasin is used therapeutically as an antihypertensive.Amino acid analysis of saralasin show the presence of the following amino acids:
Ala,Arg,His,Pro,Sar,Tyr,Val,Val
-Refer to Exhibit 26-5.N-Terminal analysis by the Edman method shows saralasin contains sarcosine at the N-terminus.Partial hydrolysis of saralasin with dilute hydrochloric acid yields the following fragments:
Tyr−Val−His
Sar−Arg−Val
His−Pro−Ala
Val−Tyr−Val
Arg−Val−Tyr
What is the structure of saralasin?

Question

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The Answer of Exhibit 26-5
Refer to the data below to answer the following question(s):
The octapeptide saralasin is a specific antagonist of angiotensin II.A derivative of saralasin is used therapeutically as an antihypertensive.Amino acid analysis of saralasin show the presence of the following amino acids:
Ala,Arg,His,Pro,Sar,Tyr,Val,Val
-Refer to Exhibit 26-5.N-Terminal analysis by the Edman method shows saralasin contains sarcosine at the N-terminus.Partial hydrolysis of saralasin with dilute hydrochloric acid yields the following fragments:
Tyr−Val−His
Sar−Arg−Val
His−Pro−Ala
Val−Tyr−Val
Arg−Val−Tyr
What is the structure of saralasin?

Exhibit 26-5 Refer to the Data Below to Answer the Following Question(s)