Exhibit 23-3
Consider the data below to answer the following question(s):
The Friedlander Quinoline Synthesis,first reported in 1882,is the base-catalyzed condensation of 2-aminobenzaldehydes with ketones to form quinoline derivatives.
-Refer to Exhibit 23-3.The second step of the Friedlander Quinoline Synthesis is a nucleophilic addition of a primary amine to a ketone yielding an imine.Write the complete stepwise mechanism for this imine forming reaction.Show all electron flow with arrows and show all intermediate structures.

Question

Exhibit 23-3
Consider the data below to answer the following question(s):
The Friedlander Quinoline Synthesis,first reported in 1882,is the base-catalyzed condensation of 2-aminobenzaldehydes with ketones to form quinoline derivatives. 
-Refer to Exhibit 23-3.The second step of the Friedlander Quinoline Synthesis is a nucleophilic addition of a primary amine to a ketone yielding an imine.Write the complete stepwise mechanism for this imine forming reaction.Show all electron flow with arrows and show all intermediate structures.

Quizplus · Accepted Answer

The Answer of Exhibit 23-3
Consider the data below to answer the following question(s):
The Friedlander Quinoline Synthesis,first reported in 1882,is the base-catalyzed condensation of 2-aminobenzaldehydes with ketones to form quinoline derivatives. 
-Refer to Exhibit 23-3.The second step of the Friedlander Quinoline Synthesis is a nucleophilic addition of a primary amine to a ketone yielding an imine.Write the complete stepwise mechanism for this imine forming reaction.Show all electron flow with arrows and show all intermediate structures.

Exhibit 23-3 Consider the Data Below to Answer the Following Question(s)