What are the characteristic changes in the brain with Alzheimer's disease?

Question

Quizplus · Accepted Answer

Alzheimer's disease is characterized by cortical atrophy which leads to the shrinking of the brain. Plaques and neurofibrillary tangles are also found in the brain tissue causing it to impair conduction. These changes ultimately lead to the deterioration in cognitive and functional abilities.

Answer: B, C, D
 The other answer choices are incorrect as they do not accurately describe the characteristic changes in the brain with Alzheimer's disease. There is no evidence of increased ACH or decreased GABA and serotonin levels in Alzheimer's disease. Additionally, while obstruction of small arteries may occur with some types of dementia, it is not a characteristic change specific to Alzheimer's disease. Similarly, vacuoles are not found in Alzheimer's disease; they are characteristic of other neurodegenerative disorders such as Creutzfeldt-Jakob disease.

What Are the Characteristic Changes in the Brain with Alzheimer's