What causes elevated serum levels of AST and ALT during the preicteric stage of hepatitis?

Question

Quizplus · Accepted Answer

Elevated serum levels of AST and ALT during preicteric stage of hepatitis are due to necrosis of liver cells, resulting in leakage of these enzymes into the bloodstream.

Option A is not the correct choice because while viral infections can cause systemic effects, they do not directly affect liver enzymes.
Option B is not the correct choice because obstruction of bile ducts and malabsorption can lead to jaundice, but typically do not elevate AST and ALT levels. 
Option D is not the correct choice because ammonia toxicity is associated with decreased liver function and altered mental status, but does not directly cause elevated AST and ALT levels.

What Causes Elevated Serum Levels of AST and ALT During