Which factors contribute to ascites in patients with cirrhosis?

Question

Quizplus · Accepted Answer

Ascites in patients with cirrhosis is primarily caused by portal hypertension, which leads to increased hydrostatic pressure in the portal system and fluid leaking into the peritoneal cavity. This is exacerbated by a deficit of albumin, which reduces oncotic pressure in the blood vessels and allows more fluid to leak out. Increased aldosterone also contributes to fluid retention and sodium reabsorption, further exacerbating ascites in cirrhosis patients. Severe anemia, increased serum bilirubin, hypokalemia, increased serum ammonia, hyperproteinemia, and persistent hypotension may all be seen in patients with cirrhosis, but they do not directly contribute to the development of ascites.

Which Factors Contribute to Ascites in Patients with Cirrhosis