Which of the following drugs is least likely to increase the incidence of osteoporosis?

Question

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Furosemide (Lasix) is a loop diuretic commonly used to treat fluid retention and hypertension. It does not have a known effect on bone metabolism and is therefore least likely to increase the risk of osteoporosis. Heparin can cause bone loss by increasing the activity of osteoclasts, the cells that break down bone. Lithium, cisplatin, and phenytoin have all been associated with an increased risk of osteoporosis through various mechanisms.

Which of the Following Drugs Is Least Likely to Increase