Tumor necrosis factor (TNF)was developed by recombinant DNA synthesis.By what mechanism does etanercept affect the pathology of RA?

Question

Quizplus · Accepted Answer

Etanercept is a biological drug that works by binding to TNF-alpha and preventing it from binding to its receptors. This blocks the inflammatory cascade initiated by TNF-alpha, thereby lowering circulating cytokines and reducing the pathology of RA. Therefore, option C is the most appropriate answer. Option A is incorrect because etanercept is a fusion protein that targets both the human and murine TNF-alpha. Option B is incorrect because etanercept does not block the action of interleukin-1. Option D is incorrect because etanercept does not interfere with collagen biosynthesis.

Tumor Necrosis Factor (TNF)was Developed by Recombinant DNA Synthesis