Some People Are Poor Metabolizers of Certain Drugs

Some people are poor metabolizers of certain drugs.In the case of clopidogrel,which is activated by the liver,which statement about poor metabolizers is true?

A) Poor metabolizers of clopidogrel do not efficiently convert it to its active form and thus may not receive its benefits.
B) Poor metabolizers may not metabolize clopidogrel and may instead develop toxic effects at therapeutic dosages.
C) The effects of clopidogrel are not changed in poor metabolizers.
D) Poor metabolizers require lower doses of clopidogrel in order to avoid toxic effects.