Which of the Following Is NOT True of Parasympathomimetic Medications

Which of the following is NOT true of parasympathomimetic medications?

A) Cholinergic medications produce actions similar to acetylcholine, such as increased peristalsis, increased body secretions, and increased muscle strength, and are popular agents used with ocular treatments.
B) Direct-acting medications mimic acetylcholine and are pharmacologically ineffective due to the short time of action.
C) Cholinergic medications should not be combined with heart medications or antibiotics.
D) Indirect-acting cholinergics act on receptor sites to inhibit cholinesterase and thus allow collection of acetylcholine at receptor sites.
E) Cholinergic medications have few side effects and are considered safe for use in most patients.