Antibiotics of the mid-20th century were from refined plant sources, while those today come from many sources including animals and chemicals as well as plants.

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Antibiotics from the mid-20th century were primarily derived from plants such as penicillin from the Penicillium mold. However, antibiotics in modern times are derived from various sources including animals, bacteria, fungi, and synthetic chemicals.

Antibiotics of the Mid-20th Century Were from Refined Plant Sources