Jamie is a 24-year-old female with a urinary tract infection. She is healthy, afebrile, and her only drug allergy is sulfa, which gives her a rash. An appropriate first-line antibiotic choice for her would be:

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Ciprofloxacin is a first-line treatment for uncomplicated urinary tract infections (UTIs) in adults who do not have any contraindications to its use. Trimethoprim/sulfamethoxazole would normally be considered, but it is contraindicated due to Jamie's sulfa allergy. Azithromycin is not typically used for UTIs, and while ceftriaxone could be used in certain situations, it is not the first-line oral therapy for uncomplicated UTIs.

Jamie Is a 24-Year-Old Female with a Urinary Tract Infection