Newborns' (Neonates') and Premature Infants' Medication Needs Are Different from Those

Newborns' (neonates') and premature infants' medication needs are different from those of older infants and children, because their

A) kidneys and some endocrine systems are not mature, thus metabolism and excretion are impaired.
B) nervous systems and blood-brain barriers are not mature at birth, thus their nervous systems are more susceptible to the effects of medications.
C) bodies have impaired immune systems, leaving them vulnerable to infections.
D) kidneys, some endocrine systems, nervous systems, and blood-brain barriers are not mature.