The use of controlled experiments using particular substances to test hypotheses is most likely to be found in:

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Controlled experiments using particular substances are a key feature of chemistry, as chemists use experiments to test hypotheses about the properties, behavior, and interactions of chemicals. Economics, history, and the humanities rely more on observational studies and the analysis of historical or cultural data, rather than experiments with specific substances.

The Use of Controlled Experiments Using Particular Substances to Test