Which of the following pathways for complement activation is generally dependent upon the formation of antigen-antibody complexes?

Question

Quizplus · Accepted Answer

The classical pathway is generally dependent upon the formation of antigen-antibody complexes. The binding of C1q to the Fc region of an antibody bound to an antigen initiates the classical pathway. The alternative pathway is activated by microbial surfaces, while the lectin complement pathway is activated by the binding of mannan-binding lectin to microbial surfaces. Therefore, choice A is the best answer.

Which of the Following Pathways for Complement Activation Is Generally