The body's habituation to a substance, so that higher doses are required to achieve similar effects, is known as ______.

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Tolerance is the body's habituation to a substance, so that higher doses are required to achieve similar effects. Intoxication refers to the acute effects of a substance that alter behavior, mood, and cognition. Potentiation occurs when two drugs interact in a way that enhances or intensifies the effects of one or both drugs. Substance dependence involves physical and/or psychological addiction to a substance, leading to withdrawal symptoms when the substance is withdrawn.

The Body's Habituation to a Substance, So That Higher Doses