Based on what you know about holoprosencephaly,what would you expect to happen if expression of the Sonic hedgehog gene was inhibited during development of the forebrain in humans?
A) Formation of nostrils in place of eyes
B) Formation of a single cerebral hemisphere
C) Development of a duplicate pair of eyes
D) Development of a duplicate pair of ears
E) Abnormally high levels of cholesterol

Question

Quizplus · Accepted Answer

Holoprosencephaly is a developmental disorder where the forebrain fails to properly divide into two hemispheres. The Sonic hedgehog gene is involved in the signaling pathways that guide this division. Inhibition of this gene could lead to the failure of the forebrain to divide and result in the formation of a single cerebral hemisphere.

Based on What You Know About Holoprosencephaly,what Would You Expect