An increase in the concentration of MyoD would most likely lead to a(n)_______ of p21 expression,which would _______ the activity of cyclin-dependent kinases (CDKs).
A) increase;increase
B) decrease;decrease
C) decrease;increase
D) decrease;have no effect on
E) increase;decrease

Question

Quizplus · Accepted Answer

MyoD is a transcription factor that promotes muscle differentiation by increasing the expression of p21, a cyclin-dependent kinase inhibitor. This increase in p21 expression would decrease the activity of CDKs, leading to cell cycle arrest and allowing differentiation to proceed.

An Increase in the Concentration of MyoD Would Most Likely