CREB is a transcription factor that regulates gene expression.It binds to DNA and activates promoters of genes involved in addictive behaviors.Researchers who compared CREB levels in the brains of a strain of rats called P rats and wild-type rats found that when P rats consumed alcohol,
A) the total levels of CREB increased.
B) the total levels of CREB decreased.
C) the total levels of CREB remained the same.
D) levels of phosphorylated CREB increased.
E) levels of phosphorylated CREB decreased.

Question

Quizplus · Accepted Answer

The comparison of CREB levels in P rats (known to consume high amounts of alcohol) and wild-type rats after alcohol consumption showed that levels of phosphorylated CREB increased. This suggests that CREB becomes activated in response to alcohol intake in P rats.

CREB Is a Transcription Factor That Regulates Gene Expression