In eukaryotic cells, a negative regulator or silencer
A) is made of DNA.
B) binds to the enhancer region to block transcription.
C) is located both upstream and downstream from the promoter.
D) binds to the operator to block RNA polymerase.
E) binds to a repressor protein to reduce transcription rates.

Question

Quizplus · Accepted Answer

In eukaryotic cells, a negative regulator or silencer binds to a repressor protein to reduce transcription rates. This is typically done by blocking the binding of transcription factors or RNA polymerase to the promoter region. Option A is incorrect because a DNA sequence alone cannot regulate transcription without interacting with regulatory proteins. Option B is incorrect because an enhancer region is typically bound by transcription factors to increase transcription. Option C is incorrect because a silencer sequence can be located both upstream and downstream from the promoter, but it is not necessary for it to be in both locations. Option D is incorrect because an operator sequence is typically found in prokaryotic cells, and is not commonly used in eukaryotic gene regulation.

In Eukaryotic Cells, a Negative Regulator or Silencer