In eukaryotes,ribosomes become associated with endoplasmic reticulum membranes when a signal sequence
A) on the mRNA interacts with a receptor protein on the membrane.
B) on the ribosome interacts with a receptor protein on the membrane.
C) at the amino terminus of the protein being synthesized interacts with a receptor protein on the ribosome.
D) on the protein being synthesized interacts with a signal recognition particle and both bind to the endoplasmic reticulum.
E) on the mRNA passes through a pore in the membrane.

Question

Quizplus · Accepted Answer

The correct answer is D. In eukaryotes, ribosomes become associated with endoplasmic reticulum membranes when a signal sequence on the protein being synthesized interacts with a signal recognition particle (SRP), which then binds to a receptor protein on the endoplasmic reticulum membrane. This interaction causes the ribosome to move close to the membrane and to anchor onto it, allowing the protein to be synthesized directly into the lumen of the endoplasmic reticulum.

In Eukaryotes,ribosomes Become Associated with Endoplasmic Reticulum Membranes When a Signal