Both the father and husband of Queen Victoria of England were not affected by the X-linked disease hemophilia,but her son Leopold was affected,as were many of the royal grandsons and great grandsons who were descended from her daughters.The mutation that caused hemophilia in Leopold and other male descendants probably arose as a _______ mutation in _______.

Question

Quizplus · Accepted Answer

The mutation that causes hemophilia would have been present in the germline cells of Queen Victoria, meaning it would have been passed down to her offspring. Prince Albert was not affected by hemophilia, so it is unlikely that the mutation arose in his germline cells. Somatic mutations occur in non-reproductive cells and are not passed down to offspring. Leopold himself could not have been the site of the mutation, as he inherited it from his mother. Therefore, the most likely scenario is that Queen Victoria herself had the mutation in her germline cells.

Both the Father and Husband of Queen Victoria of England