Which Statement About Peripheral Membrane Proteins Is True

Which statement about peripheral membrane proteins is true?

A) They have hydrophobic regions within the lipid portion of the bilayer.
B) They have hydrophilic regions that protrude in aqueous environments on both sides of the membrane.
C) They frequently flip from one side of the bilayer to the other.
D) They control the rate of simple diffusion.
E) Their polar regions interact with complementary regions of integral membrane proteins.