For a G protein to play its part in moving events forward in a signal pathway,
A) GDP must be released,and a GTP must occupy the nucleotide-binding site.
B) GTP must be released,and a GDP must occupy the nucleotide-binding site.
C) cGMP must occupy the otherwise empty nucleotide-binding site.
D) cGMP must leave the otherwise occupied nucleotide-binding site.
E) it must be linked to a specific intracellular receptor.

Question

Quizplus · Accepted Answer

For a G protein to become activated and move events forward in a signal pathway, GDP must first be released from the nucleotide-binding site and replaced with GTP. This allows the G protein to undergo a conformational change and interact with downstream effector molecules.

For a G Protein to Play Its Part in Moving