You have duplicated the threonine to isoleucine metabolic pathway and want to determine the saturation level of threonine.You slowly add increasing amounts of threonine and observe that the reaction rate initially increases slowly and then decreases.You also note that increasing the amount of isoleucine decreases the rate of the reaction.You determine that the pathway is thus regulated by

Question

Quizplus · Accepted Answer

The observation that increasing the amount of isoleucine decreases the rate of the reaction suggests that the pathway is subject to feedback inhibition, where the end product of the pathway (isoleucine) regulates the pathway by inhibiting an enzyme earlier in the pathway. The initial slow increase and later decrease in reaction rate with increasing threonine concentration also suggests feedback inhibition, as an increase in threonine concentration may eventually lead to the production of excess isoleucine, which then inhibits the pathway.

You Have Duplicated the Threonine to Isoleucine Metabolic Pathway and Want