A ________ assay is most useful for determining the viability of a viral preparation.

Question

Quizplus · Accepted Answer

A plaque assay is the best choice for determining the viability of a viral preparation. Plaque assay is a technique used to visualize and count infectious viral particles, in which a virus is grown in cell culture, and then diluted over a series of tubes, mixed with a particular cell type, and plated onto a culture plate. The virus will infect and kill cells, creating visible zones, or plaques, of dead cells. The number of plaques can be counted to estimate the number of infectious virus particles present in the sample.

A ________ Assay Is Most Useful for Determining the Viability