After the Boston Marathon, seven runners were admitted to local hospitals with suspected myoglobinuria (rhabdomyolysis). What is the most likely cause of myoglobinuria in these athletes?

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Excessive muscular activity, such as that experienced during a marathon, can cause rhabdomyolysis, a condition in which muscle breakdown releases myoglobin into the bloodstream, leading to myoglobinuria. This can cause kidney damage and other serious health complications. Tendon injury, undiagnosed hypertension, and undetected cardiac abnormalities are not directly linked to myoglobinuria.

After the Boston Marathon, Seven Runners Were Admitted to Local