The goal of antibiotic therapy in a patient with sepsis is to narrow the therapy to one narrow-spectrum antibiotic. What purpose does this goal serve in the patient's care to aid in the prevention of antibiotic resistance?

Question

Quizplus · Accepted Answer

1. Patients with sepsis have abnormal renal and hepatic function; the pharmacist should be consulted to ensure that the prescribed dose results in serum concentrations that are both clinically effective and minimally toxic.
2. The goal is to narrow therapy once culture results identify the infecting organism. This has several benefits, including decreased cost, prevention of the development of resistance, and reduced toxicity.
3. This is not a true statement.
4. One antibiotic can ultimately reduce the patient's costs, but that is not the only purpose of this goal.

The Goal of Antibiotic Therapy in a Patient with Sepsis