Myasthenia gravis is a collection of muscle disorders that cause muscle fatigue and weakness. What is the major mechanism? A) overproduction of acetylcholinesterase B) autoimmune destruction of nicotinic acetylcholine receptors C) demyelination of axons in motor pathways D) autoimmune destruction of L-type Ca²⁺ channels. E) a tumor that overproduces acetylcholine

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Myasthenia gravis is an autoimmune disorder where antibodies attack and destroy nicotinic acetylcholine receptors (nAChR) on the muscle cell membrane. This reduces the number of functional receptors available and impairs neuromuscular transmission, leading to muscle fatigue and weakness.

Myasthenia Gravis Is a Collection of Muscle Disorders That Cause