Which of the following statements about acetylcholine is correct?
A) Acetylcholine binds to nicotinic and muscarinic receptors.
B) Acetylcholine binds to adrenergic receptors.
C) Acetylcholine synthesis is catalyzed by acetylcholinesterase
D) Acetylcholine is the neurotransmitter released by most sympathetic postganglionic neurons.
E) Acetylcholine is generally transported back into presynaptic nerve terminals without being enzymatically degraded.

Question

Quizplus · Accepted Answer

Acetylcholine binds to two types of receptors: nicotinic receptors, which are ionotropic receptors found on skeletal muscle cells and in the autonomic ganglia, and muscarinic receptors, which are metabotropic receptors found in various organs innervated by the parasympathetic nervous system. Acetylcholinesterase is the enzyme responsible for breaking down acetylcholine, not synthesizing it. Acetylcholine is not the primary neurotransmitter released by sympathetic postganglionic neurons; they typically release norepinephrine. Acetylcholine is sometimes transported back into presynaptic nerve terminals without being degraded, but it can also be enzymatically degraded by acetylcholinesterase.

Which of the Following Statements About Acetylcholine Is Correct