In 1868, Dr. Harlow wrote of Phineas Gage, "He is fitful, irreverent, indulging at times in the grossest profanity. manifesting but little deference for his fellows, impatient of restraint or advice when it conflicts with his desires." This change to the personality of Phineas Gage was the result of _______________.

Question

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The change in Phineas Gage's personality was due to damage to his prefrontal cortex, which occurred when an iron rod penetrated his skull during a railroad construction accident. This area of the brain is associated with personality, decision-making, and social behavior.