Depressed individuals are especially likely to show reduced brain activity in the

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Depressed individuals often experience reduced activity in the reward centers of the brain, such as the ventral striatum, which can contribute to decreased motivation and pleasure-seeking behaviors. Activity in the amygdala, thalamus, and frontal lobes may also be affected, but reduced reward center activity is a hallmark feature of depression.

Depressed Individuals Are Especially Likely to Show Reduced Brain Activity