Alzheimer's disease is thought to involve primarily
A)loss of neurons that secrete or respond to catecholamines.
B)loss of adrenergic neurons.
C)loss of cholinergic neurons.
D)loss of neurons that secrete or respond to dopamine.
E)tumors that produce excess serotonin.

Question

Quizplus · Accepted Answer

Alzheimer's disease involves primarily the loss of cholinergic neurons, which are responsible for the production and release of the neurotransmitter acetylcholine. This leads to a decrease in acetylcholine levels in the brain and results in the memory and cognitive impairments that are characteristic of the disease. While other neurotransmitter systems may also be affected in Alzheimer's disease, the loss of cholinergic function is thought to be the primary underlying pathology.

Alzheimer's Disease Is Thought to Involve Primarily