Azetazolamide (Diamox)is a diuretic.It functions by blocking the activity of carbonic anhydrase inside kidney tubule cells.This slows the formation of carbonic acid.By slowing the formation of hydrogen ions in the cells of the tubule,sodium reabsorption is also slowed.This results in the diuretic effect.Select from the following list the possible side-effects of Azetazolamide. (1)acidosis
(2)reduced movement of bicarbonate ion into the plasma
(3)an alkaline urine is produced
(4)respiration increases
A)1,4
B)2,3
C)1,2,3
D)2,3,4
E)1,2,3,4

Question

Quizplus · Accepted Answer

Acetazolamide inhibits carbonic anhydrase, leading to decreased bicarbonate reabsorption and increased bicarbonate excretion, causing acidosis, reduced bicarbonate in plasma, alkaline urine, and compensatory increased respiration.

Azetazolamide (Diamox)is a Diuretic