Bilirubin is a breakdown product of heme from hemoglobin in red blood cells, not from globin or bile. It does not play a role in erythropoiesis and is not found in white blood cells. When the liver's ability to process or excrete bilirubin is impaired, or when red blood cell destruction is increased, bilirubin can accumulate in the blood, leading to jaundice.

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Bilirubin

Question 52

Multiple Choice

Bilirubin

A) is found in white blood cells.
B) may be reused in erythropoiesis.
C) is formed from the globin groups of hemoglobin.
D) is made from bile.
E) may build up in the circulation and cause jaundice.

Correct Answer: