Aspirin inhibits platelet plug formation by
A) blocking the binding of platelets to collagen.
B) interfering with the synthesis of prostaglandins.
C) blocking the effects of serotonin.
D) making the platelet surface less sticky.
E) stimulating the release of heparin.

Question

Quizplus · Accepted Answer

Aspirin inhibits the enzyme cyclooxygenase, which is necessary for the synthesis of prostaglandins. Prostaglandins play a key role in the initiation of the platelet plug formation in the blood clotting process. By interfering with prostaglandin synthesis, aspirin reduces platelet aggregation and thus inhibits platelet plug formation.

Aspirin Inhibits Platelet Plug Formation by