A local anesthetic such as Novocaine decreases membrane permeability to Na+ ions.The use of this anesthetic will
A)block sensory input into the CNS.
B)enhance the development of EPSPs.
C)cause RMP to move closer to threshold.
D)cause Cl- ions to enter cells instead of Na+ ions.
E)depolarize the cell.

Question

Quizplus · Accepted Answer

Novocaine decreases membrane permeability to Na+ ions, which means that it reduces the ability of neurons to depolarize and initiate an action potential. This means that the transmission of sensory input into the CNS is blocked, resulting in anesthesia. Therefore, choice A is the correct answer. The other options are incorrect because they do not accurately describe the effect of Novocaine on membrane permeability.

A Local Anesthetic Such as Novocaine Decreases Membrane Permeability to Na