Researchers Often Use Mice to Evaluate Potential Medications for Treating

Researchers often use mice to evaluate potential medications for treating human disease.If a medication is successful in the mouse model,it then must be further tested in human clinical trials.Which of the following best explains why clinical trials are necessary?

A) Mice and humans have very different biochemistries.
B) Mice and humans live in different environments.
C) Mice are much smaller than humans.
D) Mice and humans have only 80% genetic similarity.
E) Mice and humans evolved independently of one another.