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About 1 in every 100 Caucasians suffers from celiac disease.These individuals have severe allergic responses and digestive problems when they eat certain grains.Their illness is caused specifically by gluten,a protein found in wheat,barley,and rye.Treatments for this disease often rely on dietary supplements that contain protein-degrading enzymes that can break down the gluten during normal digestion,making it harmless.
One such enzyme is called AN-PEP (an abbreviation for prolyl endoprotease),and it is isolated from the fungus Aspergillus niger.Various research groups are investigating ways to use this enzyme to treat humans.One group is researching the possibility of adding the gene for AN-PEP to wheat so that gluten protein will be detoxified at the very source.
If the AN-PEP gene were somehow inserted into the intestinal cells of celiac patients,this would be a form of

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If the AN-PEP gene were inserted into the intestinal cells of celiac patients, it would be a form of gene therapy as it involves the manipulation of genetic material to treat a disease. This option is the most appropriate as the other choices, hereditary mutation and cloning, do not accurately describe this process. Hereditary mutation refers to changes that occur naturally in genetic material and not through artificial manipulation, while cloning involves the replication of an entire organism or individual cells and not just the insertion of a single gene.

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