DNA methylation may be a significant mode of genetic regulation in eukaryotes.Methylation refers to ________.
A) altering RNA polymerase activity by methylation
B) changes in DNA-DNA hydrogen binding
C) altering translational activity,especially of highly methylated tRNAs
D) alteration of DNA polymerase activity by addition of methyl groups to glycine residues
E) addition of methyl groups to the cytosine of CG doublets
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