One of the primary reasons for generating a large number of clones in a eukaryotic genomic library is that ________.
A) each cosmid replicates in coordination with the host chromosome
B) lysogenic phages continue to integrate their DNA into the host chromosome, thus reducing the number of desired recombinant clones
C) each vector can take up only a relatively small fraction of the eukaryotic DNA
D) each ligation product is sequence specific
E) the host range of the vector is limited

Question

Quizplus · Accepted Answer

Each vector has a limited capacity of DNA it can take up, therefore generating a large number of clones increases the chance of capturing a representative portion of the eukaryotic genome.

One of the Primary Reasons for Generating a Large Number