In an aqueous solution, protein conformation is determined by two major factors. One is the formation of the maximum number of hydrogen bonds. The other is the:
A) formation of the maximum number of hydrophilic interactions.
B) maximization of ionic interactions.
C) minimization of entropy by the formation of a water solvent shell around the protein.
D) placement of hydrophobic amino acid residues within the interior of the protein.
E) placement of polar amino acid residues around the exterior of the protein.

Question

Quizplus · Accepted Answer

In an aqueous solution, hydrophobic amino acid residues tend to cluster together to minimize their interaction with water molecules, therefore the placement of hydrophobic amino acid residues within the interior of the protein is crucial for protein stability and conformation.

In an Aqueous Solution, Protein Conformation Is Determined by Two