Which statement about intrinsically disordered proteins is true?
A)They contain small hydrophobic cores.
B)They represent misfolded conformations of cellular proteins.
C)They have no stable three-dimensional structure and therefore have no cellular function.
D)They are responsible for proteostasis.
E)They can interact with multiple protein-binding partners and are central to protein interaction networks.

Question

Quizplus · Accepted Answer

Intrinsically disordered proteins (IDPs) lack a stable three-dimensional structure, but they serve important functions in cells. They are involved in protein-protein interactions and can interact with multiple protein-binding partners, making them central to protein interaction networks. They do not have small hydrophobic cores and are not misfolded conformations of cellular proteins. While they do not have a stable three-dimensional structure, they can adopt specific conformations when bound to their binding partners. Therefore, IDPs play a critical role in many biological processes.

Which Statement About Intrinsically Disordered Proteins Is True