In the "Activation" of an Amino Acid for

In the "activation" of an amino acid for

A) leucine can be attached to tRNA^Phe,by the aminoacyl-tRNA synthetase specific for leucine.
B) methionine is first formylated,then attached to a specific tRNA.
C) the amino acid is attached to the 5' end of the tRNA through a phosphodiester bond.
D) there is at least one specific activating enzyme and one specific tRNA for each amino acid.
E) two separate enzymes are required,one to form the aminoacyl adenylate,the other to attach the amino acid to the tRNA.