Which of these statements about the regulation of cholesterol synthesis is not true?
A) Cholesterol acquired in the diet has essentially no effect on the synthesis of cholesterol in the liver.
B) Failure to regulate cholesterol synthesis predisposes humans to atherosclerosis.
C) High intracellular cholesterol stimulates formation of cholesteryl esters.
D) Insulin stimulates HMG-CoA reductase.
E) Some metabolite or derivative of cholesterol inhibits HMG-CoA reductase.
Correct Answer:
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