If glucose labeled with ¹⁴C at C-2 were metabolized in the liver,the first radioactive pyruvate formed would be labeled in:

Question

Quizplus · Accepted Answer

Glucose labeled at C-2 with ¹⁴C will result in the formation of pyruvate through glycolysis. During glycolysis, glucose is converted to two molecules of pyruvate via a series of enzymatic reactions. The carbonyl carbon of pyruvate is derived from the carbonyl carbon of glucose (C-2). Therefore, the first radioactive pyruvate formed would be labeled at its carbonyl carbon.

If Glucose Labeled with 14C at C-2 Were Metabolized in the Liver,the

If Glucose Labeled with ¹⁴C at C-2 Were Metabolized in the Liver,the