All of the following contribute to the large,negative,free-energy change upon hydrolysis of "high-energy" compounds except:
A)electrostatic repulsion in the reactant.
B)low activation energy of forward reaction.
C)stabilization of products by extra resonance forms.
D)stabilization of products by ionization.
E)stabilization of products by solvation.

Question

Quizplus · Accepted Answer

A low activation energy would actually favor the forward reaction and contribute to a larger negative free energy change upon hydrolysis of "high-energy" compounds. The other choices, electrostatic repulsion, stabilization of products by extra resonance forms, stabilization of products by ionization, and stabilization of products by solvation all contribute to the large, negative, free-energy change observed during hydrolysis of "high-energy" compounds.

All of the Following Contribute to the Large,negative,free-Energy Change Upon